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Recent investigations have indicated that individuals with advanced depression exhibit a significant imbalance in OS, characterized by elevated levels of free 8-iso-prostaglandins (a lipid peroxidation product) and declined activity of glutathione peroxidase, an important antioxidant defense mechanism (141–143)

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doi: 10.1016/bs.apcsb.2014.11.002 [DOI] [PubMed] [Google Scholar] 2.Galisteo-González F, Molina-Bolívar JA